Ultraviolet photofragmentation of biomolecular ions

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Ultraviolet photofragmentation of biomolecular ions.

Mass spectrometric identification of all types of molecules relies on the observation and interpretation of ion fragmentation patterns. Peptides, proteins, carbohydrates, and nucleic acids that are often found as components of complex biological samples represent particularly important challenges. The most common strategies for fragmenting biomolecular ions include low- and high-energy collisio...

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Photofragmentation of Isoleucine by Vacuum Ultraviolet Photoionization

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Gas-phase conformation-specific photofragmentation of proline-containing peptide ions.

Singly-protonated proline-containing peptides with N-terminal arginine are photodissociated with vacuum ultraviolet (VUV) light in an ESI linear ion trap/orthogonal-TOF (LIT/o-TOF). When proline is the nth residue from the N-terminus, unusual b(n) + 2 and a(n) + 2 ions are observed. Their formation is explained by homolytic cleavage of the C(alpha)-C bond in conjunction with a rearrangement of ...

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Vacuum ultraviolet photofragmentation of octadecane: photoionization mass spectrometric and theoretical investigation

The photoionization and fragmentation of octadecane were investigated with infrared laser desorption/tunable synchrotron vacuum ultraviolet (VUV) photoionization mass spectrometry (IRLD/VUV PIMS) and theoretical calculations. Mass spectra of octadecane were measured at various photon energies. The fragment ions were gradually detected with the increase of photon energy. The main fragment ions w...

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The interaction of nanoscale NaCl particles with 193-nm photons is studied to better understand particle disintegration and production by ultraviolet photofragmentation. The particles are irradiated in a constrained air stream with laser fluences from 0.08 to 0.23 J /cm2 with single and multiple pulses striking the particles. The resulting particle size distributions are measured with a scannin...

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ژورنال

عنوان ژورنال: Mass Spectrometry Reviews

سال: 2009

ISSN: 0277-7037,1098-2787

DOI: 10.1002/mas.20214